52. Pharmaceutical procedure for evaluation of masticatory efficiency using pharmaceutical product as a test food.

Pharmaceutical product design using combinatorial optimization

A two-step computational method for designing new molecules in medicinal chemistry is described. In the first step, topological indices are used to develop structure-based correlations for properties of interest. Zeroth and first order connectivity indices are employed to develop linear correlations for three physical properties of interest in pharmaceutical chemistry: octanol–water partition c...

Pharmaceutical Product Liability

Product liability is one of the fastest growing and most economically significant applications of tort law. Product liability actions against pharmaceutical companies are among the most widely publicized classes of suits in the United States and Europe, prompting pharmaceutical companies to lobby vigorously for tort reform. (Nace et al., 1997). The liability burden on pharmaceutical companies h...

Treatment of Diabetic Foot Ulcer (DFU) with Pharmaceutical Product using Hirudo orientalis: A Case Report

Every 30 seconds, one lower limb amputation due to diabetes is performed in the world. This study was conducted on a 64-year-old woman with a diabetic foot on her left leg [Sci Rew1] . The patient had pain with a visual analog scale (VAS) score of 80 mm on 100 mm. This study aimed to evaluate the effect of a product derived from leeches in the treatment of DFUs. Wound grade 1 according to Wagne...

Instruction for Use of the Pharmaceutical Product

Information Modeling for Pharmaceutical Product Development

Development of a pharmaceutical product involves several inter-related steps with multiple decisions requiring iterative improvements. Large amounts of information, including the properties of a drug substance, interactions of materials, unit operations, equipment etc, have to be gathered and used for decision making. A systematic model of the associated information is thus needed to streamline...